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Elevated von Willebrand factor levels during heavy menstrual bleeding episodes limit the diagnostic utility for von Willebrand disease

BACKGROUND: Heavy menstrual bleeding (HMB) is often the first bleeding symptom for female individuals with inherited bleeding disorders. Guidelines recommend performing the hemostatic evaluation at HMB presentation. Von Willebrand factor (VWF) levels increase with stress, making it unclear if VWF st...

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Detalles Bibliográficos
Autores principales: Brown, Megan C., White, Michael H., Friedberg, Rachel, Woods, Kalinda, Childress, Krista, Kulkarni, Mona, Sidonio, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105159/
https://www.ncbi.nlm.nih.gov/pubmed/33977212
http://dx.doi.org/10.1002/rth2.12513