Identification of the key target profiles underlying the drugs of narrow therapeutic index for treating cancer and cardiovascular disease

An appropriate therapeutic index is crucial for drug discovery and development since narrow therapeutic index (NTI) drugs with slight dosage variation may induce severe adverse drug reactions or potential treatment failure. To date, the shared characteristics underlying the targets of NTI drugs have...

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Detalles Bibliográficos
Autores principales: Yin, Jiayi, Li, Xiaoxu, Li, Fengcheng, Lu, Yinjing, Zeng, Su, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105181/
https://www.ncbi.nlm.nih.gov/pubmed/33995923
http://dx.doi.org/10.1016/j.csbj.2021.04.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105181/
https://www.ncbi.nlm.nih.gov/pubmed/33995923
http://dx.doi.org/10.1016/j.csbj.2021.04.035

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