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Identification of the key target profiles underlying the drugs of narrow therapeutic index for treating cancer and cardiovascular disease
An appropriate therapeutic index is crucial for drug discovery and development since narrow therapeutic index (NTI) drugs with slight dosage variation may induce severe adverse drug reactions or potential treatment failure. To date, the shared characteristics underlying the targets of NTI drugs have...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105181/ https://www.ncbi.nlm.nih.gov/pubmed/33995923 http://dx.doi.org/10.1016/j.csbj.2021.04.035 |