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Migration and invasion of NSCLC suppressed by the downregulation of Src/focal adhesion kinase using single, double and tetra domain anti- CEACAM6 antibodies

Carcinoembryonic antigen-related cell adhesion molecules 6 (CEACAM6) is a cell adhesion receptor. Expression of CEACAM6 in non-small cell lung cancer (NSCLC) associated with tumor progression and metastatic condition via Src/FAK signaling pathway. We established three anti-CEACAM6 antibodies with va...

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Detalles Bibliográficos
Autores principales: Wu, Shang-Jung, Arundhathi, Arivajiagane, Wang, Hsiang-Ching, Chen, Chiao-Yun, Cheng, Tsai-Mu, Yuan, Shyng-Shiou F., Wang, Yun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105299/
https://www.ncbi.nlm.nih.gov/pubmed/33934053
http://dx.doi.org/10.1016/j.tranon.2021.101057