YAP inhibits autophagy and promotes progression of colorectal cancer via upregulating Bcl-2 expression

Colorectal cancer (CRC) is one of the most aggressive and lethal cancers. The role of autophagy in the pathobiology of CRC is intricate, with opposing functions manifested in different cellular contexts. The Yes-associated protein (YAP), a transcriptional coactivator inactivated by the Hippo tumor-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Lan, Chen, Yunhe, Cheng, Dan, He, Zhikai, Shi, Xinyi, Du, Boyu, Xi, Xueyan, Gao, Yujing, Guo, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105309/
https://www.ncbi.nlm.nih.gov/pubmed/33963173
http://dx.doi.org/10.1038/s41419-021-03722-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105309/
https://www.ncbi.nlm.nih.gov/pubmed/33963173
http://dx.doi.org/10.1038/s41419-021-03722-8

Ejemplares similares