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Applicability of pan-TRK immunohistochemistry for identification of NTRK fusions in lung carcinoma

In the last two decades, various therapies have been introduced for lung carcinoma patients, including tyrosine-kinase inhibitors for different mutations. While some of them are specific to specific tumor types, others, like NTRK1–3 fusions, are found in various solid tumors. The occurrence of an NT...

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Detalles Bibliográficos
Autores principales: Strohmeier, Simon, Brcic, Iva, Popper, Helmut, Liegl-Atzwanger, Bernadette, Lindenmann, Jörg, Brcic, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105314/
https://www.ncbi.nlm.nih.gov/pubmed/33963267
http://dx.doi.org/10.1038/s41598-021-89373-3