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Intestinal mucosa-derived DNA methylation signatures in the penetrating intestinal mucosal lesions of Crohn’s disease

The purpose of this study was to evaluate genome-wide DNA methylation changes in intestinal mucosa tissue of adult patients with Crohn's disease comprehensively. DNA methylation chip was used to analyze abnormal methylation sites among penetrating and non-penetrating intestinal mucosa tissue of...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Wang, Zhiming, Wu, Xiuwen, Wang, Gefei, Gu, Guosheng, Ren, Huajian, Hong, Zhiwu, Ren, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105344/
https://www.ncbi.nlm.nih.gov/pubmed/33963246
http://dx.doi.org/10.1038/s41598-021-89087-6