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Knockout of immunotherapy prognostic marker genes eliminates the effect of the anti-PD-1 treatment

The efficacy of immunotherapy is largely patient-specific due to heterogeneity in tumors. Combining statistic power from a variety of immunotherapies across cancer types, we found four biological pathways significantly correlated with patient survival following immunotherapy. The expression of immun...

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Detalles Bibliográficos
Autores principales: Yang, Naixue, Ji, Fansen, Cheng, Liqing, Lu, Jingzhe, Sun, Xiaofeng, Lin, Xin, Lan, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105367/
https://www.ncbi.nlm.nih.gov/pubmed/33963274
http://dx.doi.org/10.1038/s41698-021-00175-2