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Intra-Articular injection of acid-sensitive stearoxyl-ketal-dexamethasone microcrystals for long-acting arthritis therapy

Despite advances in treatment of chronic arthritis, there is still a strong need for the development of long-acting formulations that can enable local and sustained drug release at the inflamed tissues. In this work, we fabricated microcrystals of an acid-sensitive stearoxyl-ketal-dexamethasone prod...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Chen, Ziqi, Xu, Zunkai, Du, Yanyan, Han, Jianghao, Yuan, Xiaoyong, Zhang, Shubiao, Guo, Shutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105419/
https://www.ncbi.nlm.nih.gov/pubmed/33995615
http://dx.doi.org/10.1016/j.ajps.2020.07.002