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The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
Systemic lupus erythematosus is a highly complex and heterogeneous autoimmune disease mostly mediated by B cells. It is characterized by circulating self-reactive antibodies that deposit and form immune complexes in kidney, leading to irreparable tissue damage and resulting in lupus nephritis. In a...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105598/ https://www.ncbi.nlm.nih.gov/pubmed/33996261 http://dx.doi.org/10.1016/j.omtn.2021.03.019 |