Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells

Conventional dendritic cells (cDCs) are traditionally subdivided into cDC1 and cDC2 lineages. Batf3 is a cDC1-required transcription factor, and we observed that Batf3−/− mice harbor a population of cDC1-like cells co-expressing cDC2-associated surface molecules. Using single-cell RNA sequencing wit...

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Detalles Bibliográficos
Autores principales: Lukowski, Samuel W., Rødahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H., Chandra, Janin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105636/
https://www.ncbi.nlm.nih.gov/pubmed/33997687
http://dx.doi.org/10.1016/j.isci.2021.102402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105636/
https://www.ncbi.nlm.nih.gov/pubmed/33997687
http://dx.doi.org/10.1016/j.isci.2021.102402

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