Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus

Persistent cognitive and mood dysfunction is the primary CNS symptom in veterans afflicted with Gulf War Illness (GWI). This study investigated the efficacy of melatonin (MEL) for improving cognitive and mood function with antioxidant, antiinflammatory, and pro-cognitive effects in a rat model of ch...

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Detalles Bibliográficos
Autores principales: Madhu, Leelavathi N., Kodali, Maheedhar, Attaluri, Sahithi, Shuai, Bing, Melissari, Laila, Rao, Xiaolan, Shetty, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105671/
https://www.ncbi.nlm.nih.gov/pubmed/33933884
http://dx.doi.org/10.1016/j.redox.2021.101973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105671/
https://www.ncbi.nlm.nih.gov/pubmed/33933884
http://dx.doi.org/10.1016/j.redox.2021.101973

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