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Molecular dynamics simulations of Piezo1 channel opening by increases in membrane tension
Piezo1 is a mechanosensitive channel involved in many cellular functions and responsible for sensing shear stress and pressure forces in cells. Piezo1 has a unique trilobed topology with a curved membrane region in the closed state. It has been suggested that upon activation Piezo1 adopts a flattene...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105709/ https://www.ncbi.nlm.nih.gov/pubmed/33582135 http://dx.doi.org/10.1016/j.bpj.2021.02.006 |