Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure

Piezo1 forms a mechanically activated calcium-permeable nonselective cation channel that is functionally important in many cell types. Structural data exist for C-terminal regions, but we lack information about N-terminal regions and how the entire channel interacts with the lipid bilayer. Here, we...

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Detalles Bibliográficos
Autores principales: Chong, Jiehan, De Vecchis, Dario, Hyman, Adam J., Povstyan, Oleksandr V., Ludlow, Melanie J., Shi, Jian, Beech, David J., Kalli, Antreas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105715/
https://www.ncbi.nlm.nih.gov/pubmed/33582137
http://dx.doi.org/10.1016/j.bpj.2021.02.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105715/
https://www.ncbi.nlm.nih.gov/pubmed/33582137
http://dx.doi.org/10.1016/j.bpj.2021.02.003

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