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Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure
Piezo1 forms a mechanically activated calcium-permeable nonselective cation channel that is functionally important in many cell types. Structural data exist for C-terminal regions, but we lack information about N-terminal regions and how the entire channel interacts with the lipid bilayer. Here, we...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105715/ https://www.ncbi.nlm.nih.gov/pubmed/33582137 http://dx.doi.org/10.1016/j.bpj.2021.02.003 |