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CaMKII inhibition reduces arrhythmogenic Ca(2+) events in subendocardial cryoinjured rat living myocardial slices
Spontaneous Ca(2+) release (SCR) can cause triggered activity and initiate arrhythmias. Intrinsic transmural heterogeneities in Ca(2+) handling and their propensity to disease remodeling may differentially modulate SCR throughout the left ventricular (LV) wall and cause transmural differences in arr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105719/ https://www.ncbi.nlm.nih.gov/pubmed/33956073 http://dx.doi.org/10.1085/jgp.202012737 |