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Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis

Comparative sequence analysis has enabled the annotation of millions of genes from organisms across the evolutionary tree. However, this approach has inherently biased the annotation of phylogenetically ubiquitous, rather than species-specific, functions. The ecologically unusual pathogen Mycobacter...

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Detalles Bibliográficos
Autores principales: Black, Katherine A., Duan, Lijun, Mandyoli, Lungelo, Selbach, Bruna P., Xu, Weizhen, Ehrt, Sabine, Sacchettini, James C., Rhee, Kyu Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105722/
https://www.ncbi.nlm.nih.gov/pubmed/33950161
http://dx.doi.org/10.1084/jem.20191957