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Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis
Comparative sequence analysis has enabled the annotation of millions of genes from organisms across the evolutionary tree. However, this approach has inherently biased the annotation of phylogenetically ubiquitous, rather than species-specific, functions. The ecologically unusual pathogen Mycobacter...
Autores principales: | Black, Katherine A., Duan, Lijun, Mandyoli, Lungelo, Selbach, Bruna P., Xu, Weizhen, Ehrt, Sabine, Sacchettini, James C., Rhee, Kyu Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105722/ https://www.ncbi.nlm.nih.gov/pubmed/33950161 http://dx.doi.org/10.1084/jem.20191957 |
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