In vivo testing of mucus-permeating nanoparticles for oral insulin delivery using Caenorhabditis elegans as a model under hyperglycemic conditions

The aim was to evaluate the potential of mucus-permeating nanoparticles for the oral administration of insulin. These nanocarriers, based on the coating of zein nanoparticles with a polymer conjugate containing PEG, displayed a size of 260 nm with a negative surface charge and an insulin payload of...

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Detalles Bibliográficos
Autores principales: Martínez-López, Ana L., González-Navarro, Carlos J., Aranaz, Paula, Vizmanos, José L., Irache, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105877/
https://www.ncbi.nlm.nih.gov/pubmed/33996411
http://dx.doi.org/10.1016/j.apsb.2021.02.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105877/
https://www.ncbi.nlm.nih.gov/pubmed/33996411
http://dx.doi.org/10.1016/j.apsb.2021.02.020

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