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MOCCA: a flexible suite for modelling DNA sequence motif occurrence combinatorics

BACKGROUND: Cis-regulatory elements (CREs) are DNA sequence segments that regulate gene expression. Among CREs are promoters, enhancers, Boundary Elements (BEs) and Polycomb Response Elements (PREs), all of which are enriched in specific sequence motifs that form particular occurrence landscapes. We...

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Detalles Bibliográficos
Autores principales: Bredesen, Bjørn André, Rehmsmeier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105988/
https://www.ncbi.nlm.nih.gov/pubmed/33962556
http://dx.doi.org/10.1186/s12859-021-04143-2