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Itaconate ameliorates methicillin-resistant Staphylococcus aureus-induced acute lung injury through the Nrf2/ARE pathway

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) are a critical predisposing factor of sepsis in the clinic. As a product of human energy metabolism and immune response, itaconate can effectively reduce inflammation in the body. This research employed 4-octyl itaconate (4-OI) to illust...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Wu, Yaxian, Jin, Sihao, Sun, Jiaojiao, Wan, Bin-Bin, Zhang, Jiru, Wang, Yingying, Gao, Zhi-Qi, Chen, Dan, Li, Shengpeng, Pang, Qingfeng, Wang, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106008/
https://www.ncbi.nlm.nih.gov/pubmed/33987410
http://dx.doi.org/10.21037/atm-21-1448