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PGE1 triggers Nrf2/HO-1 signal pathway to resist hemin-induced toxicity in mouse cortical neurons

BACKGROUND: Prostaglandin E1 (PGE1) exerts various pharmacological effects such as membrane stabilization, anti-inflammatory functions, vasodilation, and platelet aggregation inhibition. We have previously demonstrated that PGE1 has a beneficial impact on patients suffering from intracerebral hemorr...

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Detalles Bibliográficos
Autores principales: Shen, Jiabing, Cao, Mao-Sheng, Zhou, Tingting, Chen, Ying, Liang, Jingjing, Song, Yan, Xue, Chengbin, Cao, Mao-Hong, Ke, Kaifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106031/
https://www.ncbi.nlm.nih.gov/pubmed/33987332
http://dx.doi.org/10.21037/atm-20-5839