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Inhibition of sphingosine kinase 2 down-regulates ERK/c-Myc pathway and reduces cell proliferation in human epithelial ovarian cancer

BACKGROUND: Epithelial ovarian cancer (EOC) is the leading cause of death from female cancers. In our previous study, sphingosine kinase 2 (SphK2) inhibitor was shown to display anti-EOC activities. The purpose of this study was to evaluate further the expression characteristics and clinical signifi...

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Detalles Bibliográficos
Autores principales: Dai, Lan, Wang, Wenjing, Liu, Yixuan, Song, Keqi, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106111/
https://www.ncbi.nlm.nih.gov/pubmed/33987343
http://dx.doi.org/10.21037/atm-20-6742