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circPVT1 regulates medullary thyroid cancer growth and metastasis by targeting miR-455-5p to activate CXCL12/CXCR4 signaling

BACKGROUND: Medullary thyroid cancer (MTC) represents 13.4 % of all thyroid cancers-related deaths. The treatments for MTC are very limited especially for patients with distal metastasis. Therefore, it is critical to understand the mechanisms of MTC to pursue novel therapeutic avenues. Here, we stud...

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Detalles Bibliográficos
Autores principales: Zheng, Xun, Rui, Shu, Wang, Xiao-Fei, Zou, Xiu-He, Gong, Yan-Ping, Li, Zhi-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106141/
https://www.ncbi.nlm.nih.gov/pubmed/33962657
http://dx.doi.org/10.1186/s13046-021-01964-0