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ROC1 promotes the malignant progression of bladder cancer by regulating p-IκBα/NF-κB signaling

BACKGROUND: Regulator of cullins 1 (ROC1) is an important catalytic subunit of cullin–RING E3 ligase. Nuclear factor-kappa B (NF-κB) signaling is closely related to tumor invasion and metastasis. Earlier, we reported that ROC1 was associated with a poor prognosis in patients with bladder cancer (BCa...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Zhou, Xiaoqing, Li, Peng, Ding, Mao, You, Shengjie, Xu, Zhaoyu, Ye, Junjie, Chen, Xuedong, Tan, Mingyue, Wang, Jun, Wang, Wei, Qiu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106150/
https://www.ncbi.nlm.nih.gov/pubmed/33962660
http://dx.doi.org/10.1186/s13046-021-01935-5