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Checkpoint inhibition in combination with an immunoboost of external beam radiotherapy in solid tumors (CHEERS): study protocol for a phase 2, open-label, randomized controlled trial

BACKGROUND: While the introduction of checkpoint inhibitors (CPIs) as standard of care treatment for various tumor types has led to considerable improvements in clinical outcome, the majority of patients still fail to respond. Preclinical data suggest that stereotactic body radiotherapy (SBRT) could...

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Detalles Bibliográficos
Autores principales: Spaas, Mathieu, Sundahl, Nora, Hulstaert, Eva, Kruse, Vibeke, Rottey, Sylvie, De Maeseneer, Daan, Surmont, Veerle, Meireson, Annabel, Brochez, Lieve, Reynders, Dries, Goetghebeur, Els, Van den Begin, Robbe, Van Gestel, Dirk, Renard, Vincent, Dirix, Piet, Mestdagh, Pieter, Ost, Piet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106163/
https://www.ncbi.nlm.nih.gov/pubmed/33962592
http://dx.doi.org/10.1186/s12885-021-08088-w