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The strength of selection is consistent across both domains of the MHC class I peptide-binding groove in birds

BACKGROUND: The Major Histocompatibility Complex (MHC) codes for the key vertebrate immune receptors responsible for pathogen recognition. Foreign antigens are recognized via their compatibility to hyper-variable region of the peptide-binding groove (PBR), which consists of two separate protein doma...

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Detalles Bibliográficos
Autores principales: Minias, Piotr, He, Ke, Dunn, Peter O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106206/
https://www.ncbi.nlm.nih.gov/pubmed/33964878
http://dx.doi.org/10.1186/s12862-021-01812-x