Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2

G protein–coupled receptors (GPCRs) play diverse roles in physiological processes, and hence the ligands to modulate GPCRs have served as important molecules in biological and pharmacological approaches. However, the exploration of novel ligands for GPCR still remains an arduous challenge. In this s...

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Detalles Bibliográficos
Autores principales: Takahashi, Masaki, Amano, Ryo, Ozawa, Michiru, Martinez, Anna, Akita, Kazumasa, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106294/
https://www.ncbi.nlm.nih.gov/pubmed/33911033
http://dx.doi.org/10.1073/pnas.2019497118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106294/
https://www.ncbi.nlm.nih.gov/pubmed/33911033
http://dx.doi.org/10.1073/pnas.2019497118

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