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Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2
G protein–coupled receptors (GPCRs) play diverse roles in physiological processes, and hence the ligands to modulate GPCRs have served as important molecules in biological and pharmacological approaches. However, the exploration of novel ligands for GPCR still remains an arduous challenge. In this s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106294/ https://www.ncbi.nlm.nih.gov/pubmed/33911033 http://dx.doi.org/10.1073/pnas.2019497118 |