An intracellular nanobody targeting T4SS effector inhibits Ehrlichia infection

Infection with obligatory intracellular bacteria is difficult to treat, as intracellular targets and delivery methods of therapeutics are not well known. Ehrlichia translocated factor-1 (Etf-1), a type IV secretion system (T4SS) effector, is a primary virulence factor for an obligatory intracellular...

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Detalles Bibliográficos
Autores principales: Zhang, Wenqing, Lin, Mingqun, Yan, Qi, Budachetri, Khemraj, Hou, Libo, Sahni, Ashweta, Liu, Hongyan, Han, Nien-Ching, Lakritz, Jeffrey, Pei, Dehua, Rikihisa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106314/
https://www.ncbi.nlm.nih.gov/pubmed/33903242
http://dx.doi.org/10.1073/pnas.2024102118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106314/
https://www.ncbi.nlm.nih.gov/pubmed/33903242
http://dx.doi.org/10.1073/pnas.2024102118

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