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TCF7L2 rs7903146 polymorphism association with diabetes and obesity in an elderly cohort from Brazil

BACKGROUND: Type 2 diabetes mellitus (T2DM) and obesity are complex pandemic diseases in the 21st century. Worldwide, the T allele rs7903146 in the TCF7L2 gene is recognized as a strong GWAS signal associated with T2DM. However, the association between the C allele and obesity is still poorly explor...

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Detalles Bibliográficos
Autores principales: Bride, Lais, Naslavsky, Michel, Lopes Yamamoto, Guilherme, Scliar, Marilia, Pimassoni, Lucia HS, Sossai Aguiar, Paola, de Paula, Flavia, Wang, Jaqueline, Duarte, Yeda, Passos-Bueno, Maria Rita, Zatz, Mayana, Imbroisi Valle Errera, Flávia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106398/
https://www.ncbi.nlm.nih.gov/pubmed/33996288
http://dx.doi.org/10.7717/peerj.11349