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COVIDOUTCOME—estimating COVID severity based on mutation signatures in the SARS-CoV-2 genome
Numerous studies demonstrate frequent mutations in the genome of SARS-CoV-2. Our goal was to statistically link mutations to severe disease outcome. We used an automated machine learning approach where 1594 viral genomes with available clinical follow-up data were used as the training set (797 ‘seve...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106440/ https://www.ncbi.nlm.nih.gov/pubmed/33963845 http://dx.doi.org/10.1093/database/baab020 |