COVIDOUTCOME—estimating COVID severity based on mutation signatures in the SARS-CoV-2 genome

Numerous studies demonstrate frequent mutations in the genome of SARS-CoV-2. Our goal was to statistically link mutations to severe disease outcome. We used an automated machine learning approach where 1594 viral genomes with available clinical follow-up data were used as the training set (797 ‘seve...

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Detalles Bibliográficos
Autores principales: Nagy, Ádám, Ligeti, Balázs, Szebeni, János, Pongor, Sándor, Győrffy, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106440/
https://www.ncbi.nlm.nih.gov/pubmed/33963845
http://dx.doi.org/10.1093/database/baab020

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