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The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner

BACKGROUND: The isothiocyanate sulforaphane (SFN) has multiple protein targets in mammalian cells, affecting processes of fundamental importance for the maintenance of cellular homeostasis, among which are those regulated by the stress response transcription factor nuclear factor erythroid 2 p45-rel...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Gilmour, Amy, Ahn, Young-Hoon, de la Vega, Laureano, Dinkova-Kostova, Albena T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Urban & Fischer Verlag 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106549/
https://www.ncbi.nlm.nih.gov/pubmed/31409554
http://dx.doi.org/10.1016/j.phymed.2019.153062