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DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1

DNAJB9, a member of the heat shock protein 40 family, acts as a multifunctional player involved in the maintenance of their client proteins and cellular homeostasis. However, the mechanistic action of DNAJB9 in human malignancies is yet to be fully understood. In this study, we found that ectopic re...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Youn, Kim, Young-Mi, Hong, Suntaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106677/
https://www.ncbi.nlm.nih.gov/pubmed/33966034
http://dx.doi.org/10.1038/s41419-021-03757-x