TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability

Resistance to chemotherapy remains the major cause of treatment failure in patients with colorectal cancer (CRC). Here, we identified TRIM25 as an epigenetic regulator of oxaliplatin (OXA) resistance in CRC. The level of TRIM25 in OXA-resistant patients who experienced recurrence during the follow-u...

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Detalles Bibliográficos
Autores principales: Zhou, Sha, Peng, Jianhong, Xiao, Liuniu, Zhou, Caixia, Fang, Yujing, Ou, Qingjian, Qin, Jiayi, Liu, Mengzhong, Pan, Zhizhong, Hou, Zhenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106682/
https://www.ncbi.nlm.nih.gov/pubmed/33966039
http://dx.doi.org/10.1038/s41419-021-03734-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106682/
https://www.ncbi.nlm.nih.gov/pubmed/33966039
http://dx.doi.org/10.1038/s41419-021-03734-4

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