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Silencing TAK1 reduces MAPKs-MMP2/9 expression to reduce inflammation-driven neurohistological disruption post spinal cord injury

Microglia activation post traumatic spinal cord injury (SCI) provokes accumulation of inflammatory metabolites, leading to increasing neurological disruption. Our previous studies demonstrated that blocking MAPKs pathway mitigated microglia inflammatory activation and prevented cords from neuroinfla...

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Detalles Bibliográficos
Autores principales: Jiang, Shuai, Wu, Yandan, Wu, Shunjie, Ye, Suhui, Kong, Renyi, Chang, Jie, Xia, Mingjie, Bao, Junping, Peng, Xin, Hong, Xin, Qian, Zhanyang, Li, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106686/
https://www.ncbi.nlm.nih.gov/pubmed/33966042
http://dx.doi.org/10.1038/s41420-021-00481-5