Distribution and metabolism of [(14)C]-resveratrol in human prostate tissue after oral administration of a “dietary-achievable” or “pharmacological” dose: what are the implications for anticancer activity?

BACKGROUND: The dietary polyphenol resveratrol prevents various malignancies in preclinical models, including prostate cancer. Despite attempts to translate findings to humans, gaps remain in understanding pharmacokinetic-pharmacodynamic relations and how tissue concentrations affect efficacy. Such...

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Detalles Bibliográficos
Autores principales: Cai, Hong, Scott, Edwina N, Britton, Robert G, Parrott, Emma, Ognibene, Ted J, Malfatti, Michael, Khan, Masood, Steward, William P, Brown, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106746/
https://www.ncbi.nlm.nih.gov/pubmed/33675348
http://dx.doi.org/10.1093/ajcn/nqaa414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106746/
https://www.ncbi.nlm.nih.gov/pubmed/33675348
http://dx.doi.org/10.1093/ajcn/nqaa414

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