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Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation

BACKGROUND: Improvement of radiotherapy efficacy requires better insight in the dynamic responses that occur during irradiation. Here, we aimed to identify the molecular responses that are triggered during clinically applied fractionated irradiation. METHODS: Gene expression analysis was performed b...

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Detalles Bibliográficos
Autores principales: Goedegebuure, Ruben S. A., Kleibeuker, Esther A., Buffa, Francesca M., Castricum, Kitty C. M., Haider, Syed, Schulkens, Iris A., ten Kroode, Luuk, van den Berg, Jaap, Jacobs, Maarten A. J. M., van Berkel, Anne-Marie, van Grieken, Nicole C. T., Derks, Sarah, Slotman, Ben J., Verheul, Henk M. W., Harris, Adrian L., Thijssen, Victor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106844/
https://www.ncbi.nlm.nih.gov/pubmed/33964942
http://dx.doi.org/10.1186/s13046-021-01962-2