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EMP3 mediates glioblastoma‐associated macrophage infiltration to drive T cell exclusion
BACKGROUND: The immunosuppressive tumour microenvironment is a critical factor in the initiation and progression of glioblastoma (GBM), which is characterized by an abundance of tumour-associated macrophages (TAMs) but a paucity of infiltrating T cells. In this research, we studied whether epithelia...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106853/ https://www.ncbi.nlm.nih.gov/pubmed/33964937 http://dx.doi.org/10.1186/s13046-021-01954-2 |