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EMP3 mediates glioblastoma‐associated macrophage infiltration to drive T cell exclusion

BACKGROUND: The immunosuppressive tumour microenvironment is a critical factor in the initiation and progression of glioblastoma (GBM), which is characterized by an abundance of tumour-associated macrophages (TAMs) but a paucity of infiltrating T cells. In this research, we studied whether epithelia...

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Detalles Bibliográficos
Autores principales: Chen, Qun, Jin, Jing, Huang, Xin, Wu, Fan, Huang, Hongguang, Zhan, Renya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106853/
https://www.ncbi.nlm.nih.gov/pubmed/33964937
http://dx.doi.org/10.1186/s13046-021-01954-2