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CircPVT1 up‐regulation attenuates steroid‐induced osteonecrosis of the femoral head through regulating miR‐21‐5p‐mediated Smad7/TGFβ signalling pathway

Steroid‐induced osteonecrosis of the femoral head (SIONFH) has been a common disease following corticosteroid therapy. Presently, we aim to explore the functions of circular RNA (circ) PVT1 in SIONFH rats and the underlying mechanism. Glucocorticoid (GC) was used to treat SD rats and bone marrow‐der...

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Detalles Bibliográficos
Autores principales: Hao, Yangquan, Lu, Chao, Zhang, Baogang, Xu, Zhaochen, Guo, Hao, Zhang, Gaokui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107079/
https://www.ncbi.nlm.nih.gov/pubmed/33733589
http://dx.doi.org/10.1111/jcmm.16294