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Pancreatitis severity in mice with impaired CFTR function but pancreatic sufficiency is mediated via ductal and inflammatory cells‐Not acinar cells

Mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) are an established risk factor for cystic fibrosis (CF) and chronic pancreatitis. Whereas patients with CF usually develop complete exocrine pancreatic insufficiency, pancreatitis patients with CFTR mutations have mostl...

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Detalles Bibliográficos
Autores principales: Trapp, Simon, Aghdassi, Ali A., Glaubitz, Juliane, Sendler, Matthias, Weiss, Frank Ulrich, Kühn, Jens Peter, Kromrey, Marie‐Luise, Mahajan, Ujjwal M., Pallagi, Petra, Rakonczay, Zoltán, Venglovecz, Viktória, Lerch, Markus M., Hegyi, Peter, Mayerle, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107082/
https://www.ncbi.nlm.nih.gov/pubmed/33682322
http://dx.doi.org/10.1111/jcmm.16404