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Tissue‐specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models

The two insulin receptor (IR) isoforms IR‐A and IR‐B are responsible for the pleiotropic actions of insulin and insulin‐like growth factors. Consequently, changes in IR isoform expression and in the bioavailability of their ligands will impact on IR‐mediated functions. Although alteration of IR isof...

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Detalles Bibliográficos
Autores principales: Moruzzi, Noah, Lazzeri‐Barcelo, Francesca, Valladolid‐Acebes, Ismael, Moede, Tilo, Paschen, Meike, Leibiger, Barbara, Berggren, Per‐Olof, Leibiger, Ingo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107091/
https://www.ncbi.nlm.nih.gov/pubmed/33742502
http://dx.doi.org/10.1111/jcmm.16452