Cargando…

Tissue‐specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models

The two insulin receptor (IR) isoforms IR‐A and IR‐B are responsible for the pleiotropic actions of insulin and insulin‐like growth factors. Consequently, changes in IR isoform expression and in the bioavailability of their ligands will impact on IR‐mediated functions. Although alteration of IR isof...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moruzzi, Noah, Lazzeri‐Barcelo, Francesca, Valladolid‐Acebes, Ismael, Moede, Tilo, Paschen, Meike, Leibiger, Barbara, Berggren, Per‐Olof, Leibiger, Ingo B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107091/ https://www.ncbi.nlm.nih.gov/pubmed/33742502 http://dx.doi.org/10.1111/jcmm.16452

Ejemplares similares

Diet-induced β-cell insulin resistance results in reversible loss of functional β-cell mass
por: Paschen, Meike, et al.
Publicado: (2019)

Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice
por: Leibiger, Barbara, et al.
Publicado: (2021)

Isoform-specific insulin receptor signaling involves different plasma membrane domains
por: Uhles, Sabine, et al.
Publicado: (2003)

Non-invasive cell type selective in vivo monitoring of insulin resistance dynamics
por: Paschen, Meike, et al.
Publicado: (2016)

Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes
por: Mir-Coll, Joan, et al.
Publicado: (2021)

Mitochondrial impairment and intracellular reactive oxygen species alter primary cilia morphology
por: Moruzzi, Noah, et al.
Publicado: (2022)

Alpha cell regulation of beta cell function
por: Moede, Tilo, et al.
Publicado: (2020)

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells
por: Moede, Tilo, et al.
Publicado: (2020)

Intraocular in vivo imaging of pancreatic islet cell physiology/pathology
por: Leibiger, Ingo B., et al.
Publicado: (2017)

Dynamin-mediated Nephrin Phosphorylation Regulates Glucose-stimulated Insulin Release in Pancreatic Beta Cells
por: Jeon, Jongmin, et al.
Publicado: (2012)

Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K(+) channels
por: Heitz, Benjamin A., et al.
Publicado: (2021)

Apolipoprotein CIII Reduction Protects White Adipose Tissues against Obesity-Induced Inflammation and Insulin Resistance in Mice
por: Recio-López, Patricia, et al.
Publicado: (2021)

Inward and outward currents of native and cloned K(ATP) channels (Kir6.2/SUR1) share single-channel kinetic properties
por: Bränström, Robert, et al.
Publicado: (2022)

Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling
por: Yu, Jia, et al.
Publicado: (2023)

Apolipoprotein CIII Is an Important Piece in the Type-1 Diabetes Jigsaw Puzzle
por: Valladolid-Acebes, Ismael, et al.
Publicado: (2021)

Real-Time Monitoring of Apoptosis by Caspase-3-Like Protease Induced FRET Reduction Triggered by Amyloid Aggregation
por: Paulsson, Johan F., et al.
Publicado: (2008)

Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells
por: Kabra, Uma D., et al.
Publicado: (2022)

Lowering apolipoprotein CIII protects against high-fat diet–induced metabolic derangements
por: Valladolid-Acebes, Ismael, et al.
Publicado: (2021)

Local Dexamethasone Administration Delays Allogeneic Islet Graft Rejection in the Anterior Chamber of the Eye of Non-Human Primates
por: Tun, Sai Bo Bo, et al.
Publicado: (2022)

SNAP-25b-deficiency increases insulin secretion and changes spatiotemporal profile of Ca(2+)oscillations in β cell networks
por: Daraio, Teresa, et al.
Publicado: (2017)

Pancreatic β Cells Inhibit Glucagon Secretion from α Cells: An In Vitro Demonstration of α–β Cell Interaction
por: Gu, Wenqian, et al.
Publicado: (2021)

Custom titanium sleeve for surgical treatment of mechanically assisted crevice corrosion in the well-fixed, noncontemporary stem in total hip arthroplasty
por: Leibiger, Thomas, et al.
Publicado: (2015)

Cycloalkyl Groups as Building Blocks of Artificial Carbohydrate Receptors: Studies with Macrocycles Bearing Flexible Side-Arms
por: Leibiger, Betty, et al.
Publicado: (2022)

Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic α-cells
por: Grubelnik, Vladimir, et al.
Publicado: (2020)

Crystal structures of 2-[3,5-bis(bromomethyl)-2,4,6-triethylbenzyl]isoindoline-1,3-dione and 2-{5-(bromomethyl)-3-[(1,3-dioxoisoindolin-2-yl)methyl]-2,4,6-triethylbenzyl}isoindoline-1,3-dione
por: Stapf, Manuel, et al.
Publicado: (2021)

Pancreatic Islet Blood Flow Dynamics in Primates
por: Diez, Juan A., et al.
Publicado: (2017)

Insulin modulates the frequency of Ca(2+) oscillations in mouse pancreatic islets
por: Lee, Boah, et al.
Publicado: (2017)

First Molecular Cytogenetic High Resolution Characterization of the NIH 3T3 Cell Line by Murine Multicolor Banding
por: Leibiger, Christine, et al.
Publicado: (2013)

One-Step ARMS-PCR for the Detection of SNPs—Using the Example of the PADI4 Gene
por: Ehnert, Sabrina, et al.
Publicado: (2019)

Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins
por: Yamashita, Tetsuji, et al.
Publicado: (2015)

mRNA expression of diacylglycerol kinase isoforms in insulin-sensitive tissues: effects of obesity and insulin resistance
por: Mannerås-Holm, Louise, et al.
Publicado: (2015)

Deprivation of the Periplasmic Chaperone SurA Reduces Virulence and Restores Antibiotic Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa
por: Klein, Kristina, et al.
Publicado: (2019)

Endolysosomal pathway activity protects cells from neurotoxic TDP-43
por: Leibiger, Christine, et al.
Publicado: (2018)

Insulin Receptor Isoforms in Cancer
por: Vella, Veronica, et al.
Publicado: (2018)

Structural basis for delta cell paracrine regulation in pancreatic islets
por: Arrojo e Drigo, Rafael, et al.
Publicado: (2019)

Author Correction: Structural basis for delta cell paracrine regulation in pancreatic islets
por: e Drigo, Rafael Arrojo, et al.
Publicado: (2019)

Shift of Circadian Feeding Pattern by High-Fat Diets Is Coincident with Reward Deficits in Obese Mice
por: Morales, Lidia, et al.
Publicado: (2012)

Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet
por: Molina, Judith, et al.
Publicado: (2014)

Engineering of Insulin Receptor Isoform-Selective Insulin Analogues
por: Glendorf, Tine, et al.
Publicado: (2011)

Hepatic Innervations and Nonalcoholic Fatty Liver Disease
por: Adori, Monika, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gubu3s6549rem2u3btaicfps2p