MBD2 mediates renal cell apoptosis via activation of Tox4 during rhabdomyolysis‐induced acute kidney injury

Our study investigated the role of Methyl‐CpG–binding domain protein 2 (MBD2) in RM‐induced acute kidney injury (AKI) both in vitro and in vivo. MBD2 was induced by myoglobin in BUMPT cells and by glycerol in mice. MBD2 inhibition via MBD2 small interfering RNA and MBD2‐knockout (KO) attenuated RM‐i...

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Detalles Bibliográficos
Autores principales: Sun, Tianshi, Liu, Qing, Wang, Yifan, Deng, Youwen, Zhang, Dongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107094/
https://www.ncbi.nlm.nih.gov/pubmed/33764669
http://dx.doi.org/10.1111/jcmm.16207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107094/
https://www.ncbi.nlm.nih.gov/pubmed/33764669
http://dx.doi.org/10.1111/jcmm.16207

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