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GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs

Thoracic aortic dissection (TAD) is an aortic disease associated with dysregulated extracellular matrix composition and de‐differentiation of vascular smooth muscle cells (SMCs). Growth Differentiation Factor 11 (GDF11) is a member of transforming growth factor β (TGF‐β) superfamily associated with...

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Detalles Bibliográficos
Autores principales: Ren, Kai, Li, Buying, Liu, Zhenhua, Xia, Lin, Zhai, Mengen, Wei, Xufeng, Duan, Weixun, Yu, Shiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107100/
https://www.ncbi.nlm.nih.gov/pubmed/33764670
http://dx.doi.org/10.1111/jcmm.16312