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Deletion of Smad3 protects against diabetic myocardiopathy in db/db mice

Diabetic cardiomyopathy (DCM) is a common diabetic complication characterized by diastolic relaxation abnormalities, myocardial fibrosis and chronic heart failure. Although TGF‐β/Smad3 signalling has been shown to play a critical role in chronic heart disease, the role and mechanisms of Smad3 in DCM...

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Detalles Bibliográficos
Autores principales: Dong, Li, Li, Jian‐Chun, Hu, Zhong‐Jing, Huang, Xiao‐Ru, Wang, Li, Wang, Hong‐Lian, Ma, Ronald C. W., Lan, Hui‐Yao, Yang, Si‐Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107104/
https://www.ncbi.nlm.nih.gov/pubmed/33733577
http://dx.doi.org/10.1111/jcmm.16464