Metformin attenuates synergic effect of diabetes mellitus and Helicobacter pylori infection on gastric cancer cells proliferation by suppressing PTEN expression

It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. Furthermore, diabetes mellitus (DM) may also promote the methylation status of PTEN, a tumour suppressor gene in gastric cancer (GC). It is intriguing to explore whether DM may streng...

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Detalles Bibliográficos
Autores principales: Lu, Huibin, Han, Xinwei, Ren, Jianzhuang, Ren, Kewei, Li, Zongming, Zhang, Quanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107109/
https://www.ncbi.nlm.nih.gov/pubmed/33760349
http://dx.doi.org/10.1111/jcmm.15967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107109/
https://www.ncbi.nlm.nih.gov/pubmed/33760349
http://dx.doi.org/10.1111/jcmm.15967

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