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Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing

Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. Existing methods for detecting DNA modification from nanopore sequencing data do not effectively support de novo study of unknown bacterial methylomes. In this...

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Detalles Bibliográficos
Autores principales: Tourancheau, Alan, Mead, Edward A., Zhang, Xue-Song, Fang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107137/
https://www.ncbi.nlm.nih.gov/pubmed/33820988
http://dx.doi.org/10.1038/s41592-021-01109-3