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Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing
Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. Existing methods for detecting DNA modification from nanopore sequencing data do not effectively support de novo study of unknown bacterial methylomes. In this...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107137/ https://www.ncbi.nlm.nih.gov/pubmed/33820988 http://dx.doi.org/10.1038/s41592-021-01109-3 |